Table 2 Distribution and phenotypic profile of CD13high CD105+ CD45– cells in normal versus reactive bone marrow samples
Normal BM (n = 9) | Reactive BM (n = 51) | |||
|---|---|---|---|---|
Antigenic profile | % positive cells | MFI | % positive cells | MFI |
% CD13high CD105+ CD45− cells | 0.008 (0.0004–0.04) | 0.03 (0.0007–0.6)* | ||
CD10 | 91 % | 7624 | 88 % | 6916 |
(75–97 %) | (2069–22,177) | (62–97 %) | (1883–14,821) | |
CD11b | NA | NA | NA | NA |
CD13 | 100 % | 162,716 | 100 % | 114,760 |
(100–100 %) | (58,223–260,438) | (100–100 %) | (45,582–182,771) | |
CD14 | NA | NA | NA | NA |
CD19 | NA | NA | NA | NA |
CD34 | NA | NA | NA | NA |
CD45 | NA | NA | NA | NA |
CD73 | 100 % | 7241 | 100 % | 8149 |
(100–100 %) | (3268–23,090) | (100–100 %) | (4462–16,288) | |
CD90 | 100 % | 64,102 | 100 % | 17,729* |
(100–100 %) | (12,081–260,738) | (100–100 %) | (1870–108,409) | |
CD105 | 100 % | 2598 | 100 % | 2463 |
(100–100 %) | (700–3420) | (100–100 %) | (1299–4620) | |
CD117 | NA | NA | NA | NA |
CD146 | 100 % | 733 | 100 % | 502 |
(100–100 %) | (292–2992) | (100–100 %) | (267–3054) | |
HLA-DR | 98 % | 4038 | 87 % | 2589 |
(78–100 %) | (390–11,726) | (50–100 %) | (407–15,823) | |