Fig. 4
SHED transplantation inhibits the enhanced distribution of Kupffer cells and T cells in recipient livers of CCl4-treated mice. a–c Expression of F4/80 and CD3 in recipient livers. Immunohistochemical staining with anti-F4/80 (a) and anti-CD3 antibodies (c). The F4/80-positive (b) and CD3-positive (d) area. e ELISA of recipient serum. b, d, e n = 5 for all groups. *P <0.05, **P <0.01, and ***P <0.005. Graph bars show the means ± SD. Control, olive oil-injected control group; CCl4, CCl4-treated group; CCl4 + SHED, SHED-transplanted CCl4-treated group. CCl 4 carbon tetrachloride, mIL mouse interleukin, mTGFβ1 mouse transforming growth factor β1, mTNFα mouse tumor necrosis factor alpha, SHED stem cells from human exfoliated deciduous teeth