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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Transplantation of cultured dental pulp stem cells into the skeletal muscles ameliorated diabetic polyneuropathy: therapeutic plausibility of freshly isolated and cryopreserved dental pulp stem cells

Fig. 3

Capillaries in the soleus muscles. a, b Representative photomicrographs of the histological sections in the skeletal muscles of normal and diabetic rats. Capillaries were visualized by von Willebrand factor (vWF) (a) and PECAM-1 (b). Arrows indicate vascular endothelial cells stained by vWF. Bar = 50μm. c Quantitative analysis for capillary to muscle fiber ratio of the skeletal muscles of normal and diabetic rats. Results are expressed as means ± SEM (n = 4). **P < 0.01. d Differentiation of transplanted green fluorescent protein (GFP)-expressing dental pulp stem cells (DPSCs) into vascular endothelial cells in the skeletal muscles 4 weeks after the transplantation. DPSCs from GFP-expressing rats were transplanted into hindlimb skeletal muscles in the diabetic rats. Vascular endothelial cells were visualized by PECAM-1. Bar = 50 μm

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