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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Small intestinal submucosa-derived extracellular matrix bioscaffold significantly enhances angiogenic factor secretion from human mesenchymal stromal cells

Fig. 1

Characterization of human MSCs cultured on SIS ECM. Human MSCs were characterized by tri-lineage induction, cell surface marker expression and eGFP transgene expression. Cells could readily be induced along the adipogenic (a), osteogenic (b) and chondrogenic lineage (c). Non-induced cells remained undifferentiated (d, e). f A subset of MSCs were transduced with eGFP and seeded onto SIS ECM. g MSCs stained positive by flow cytometry for the putative MSC surface markers CD73, CD90 and CD105 (red curve). Isotype control stained cells were uniformly negative (grey curve). Scale bars: a, b and f = 200 μm; ce = 100 μm

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