Human cord blood-derived platelet lysate enhances the therapeutic activity of adipose-derived mesenchymal stromal cells isolated from Crohn’s disease patients in a mouse model of colitis

Table 1 Histological damage score: quantitative evaluation of histological damage in study mice

Histological damage score was blindly determined from hematoxylin and eosin-stained paraffin sections of mouse colons harvested at day +22. Ten sections from each mouse and at least four mice for each group were evaluated. Data were presented as mean ± standard error of the mean (SEM). Histology was scored as indicated in Material and methods and in Additional file 3. Histological score represents the sum of the epithelial damage and infiltration score, ranging from 0 (unaffected) to 8 (severe colitis)
*Significant differences vs. DSS+PBS group, p <0.05
adCD-MSC mesenchymal stromal cell isolated from adipose tissue of Crohn’s disease patients, DSS dextran sulfate sodium, hCBPL human umbilical cord blood-derived platelet lysate, PBS phosphate saline buffer

ISSN: 1757-6512