Fig. 6
MSC-CM reduces epithelial mesenchymal transition-like phenomenon in primary trabecular cells. Effect of MSC-CM on transforming growth factor beta 2 (TGF-β2) induced collagen-3 (COL-3) a, collagen-4 (COL-4) b, and alpha-smooth muscle actin (α-SMA) c mRNA modification on hTM. The results are normalized to reference hypoxanthine guanine phosphoribosyltransferase (HPRT) genes. *p <0.01, **p <0.001, and ***p <0.0001 vs. control culture condition; #p <0.05, ##p <0.01, ###p <0.001, and ####p <0.0001 vs. TGF-β2 condition; §p <0.01 and §§p <0.0001 vs. MSC-CM condition (n = 5). MSC-CM conditioned medium of mesenchymal stem cells