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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: 1H-pyrrole-2,5-dione-based small molecule-induced generation of mesenchymal stem cell-derived functional endothelial cells that facilitate rapid endothelialization after vascular injury

Fig. 3

The morphology and function of the iMDFEC-transplanted carotid artery have greater similarity to those of intact blood vessels compared with those of the MSC-transplanted carotid artery. a The innermost layer of explanted carotid arteries was examined by using a scanning electron microscope. b Relaxation profiles of acetylcholine-stimulated carotid artery segments. The acetylcholine-induced relaxation responses are expressed as the percentage of the maximal contractions in response to 50 K+ solution. *P < 0.05. c Blood flow was measured for each group. *P < 0.05 compared with the control. G-MSC gingival mesenchymal stem cell, iMDFEC induced mesenchymal stem cell-derived functional endothelial cell, MSC mesenchymal stem cell

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Stem Cell Research & Therapy

ISSN: 1757-6512