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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Differentially expressed microRNAs in bone marrow mesenchymal stem cell-derived microvesicles in young and older rats and their effect on tumor growth factor-β1-mediated epithelial-mesenchymal transition in HK2 cells

Fig. 3

Effect of MVs and miRNAs on the inhibitory effect of TGF-β1 on the EMT in HK2 cells. a, c Western blot analysis of E-cadherin and α-SMA expression in HK2 cells under TGF-β1 stimulation co-cultured with Y-MV /O-MV or pre-transfection with miR-872, miR-344, miR-294, miR-133b -3p, and miR-control mimic. β-actin was used as internal control. b, d Quantification of E-cadherin and α-SMA protein levels in HK2 cells from each experimental group. **P < 0.05; n =3. α-SMA alpha-smooth muscle actin, EMT epithelial-mesenchymal transition, MV microvesicle, TGF-β1 transforming growth factor-beta 1

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