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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Mesenchymal stromal cells loaded with paclitaxel induce cytotoxic damage in glioblastoma brain xenografts

Fig. 4

Cytotoxic effect of PTX on U87MG brain xenografts. PTX released into the tumor microenvironment by PTX-loaded MSCs causes cytotoxic effect to the U87MG cells resulting in aberrant, multinucleated tumor cells (scale bars = 10 μm) (a). The percentage of multinucleated U87MG cells directly relates to the percentage of PTX-loaded MSCs on the total number of cells per field (b). MSC mesenchymal stem/stromal cell, PTX paclitaxel, r Pearson correlation coefficient

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