Fig. 3

MenSCs modulate the response of the host immune system to sepsis. At 24 and 40 hours after CLP-induced sepsis and treatment administration, blood samples were obtained to determine the serum concentration of the inflammatory cytokines (a) TNF-α, (b) MCP-1, (c) IL-6, and (d) IL-10 using a Cytometric Bead Array and analyzed by flow cytometry (sham, n = 6; saline, n = 3–11; AB, n = 4–6; MenSCs, n = 5–6; MenSCs + AB, n = 6). Histograms represent the mean ± standard error. AB antibiotics, CLP cecal ligation and puncture, IL interleukin, MCP-1 monocyte chemoattractant protein-1, MenSC menstrual derived mesenchymal stem cells, ns non-significant, TNF-α tumor necrosis factor-alpha