Fig. 5

MenSCs alone or in combination with antibiotic treatment promote bacterial clearance in CLP-induced sepsis in mice. Blood, peritoneal fluid, and spleen were obtained 24 hours after administration of the different treatments (sham, n = 6; saline, n = 11; AB, n = 6; MenSCs, n = 5; MenSCs + AB, n = 6). Bacterial loads were determined after incubating at 37 °C overnight and are expressed as CFUs per milliliter. a Bacterial load in blood. b Bacterial load in peritoneal fluid. c Bacterial load in spleen. Data are presented as mean ± standard error. AB antibiotics, CFU colony-forming unit, CLP cecal ligation and puncture, MenSCs menstrual derived mesenchymal stem cells, ns non-significant