Fig. 1

In vivo tracking systemically injected Luc-MSCs. a, b During the first hour following the injection, Luc-MSCs spread throughout the whole body via circulating system, and high concentrations of Luc-MSCs were observed in limbs, lungs, and oral cavity. c, d After about 1 hour following the injection, high concentrations of Luc-MSCs were observed only at the lung site, but no signal was observed at limbs, the oral cavity, and other parts of the body. e At day 4 following the injection, one mouse was terminated, and strong signals were observed at excised lungs, but no signal was observed on the excised fractured femur and other organs. f At day 11 following the injection, another mouse was terminated; no signal was observed throughout the whole body, including the lung site. Luc-MSC Luciferase labeled mesenchymal stem cell