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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Enhanced angiogenesis in ischemic skeletal muscle after transplantation of cell sheets from baculovirus-transduced adipose-derived stromal cells expressing VEGF165

Fig. 5

Effect of VEGF-expressing CS, mock-transduced CS or ADSC suspension on perfusion in the limb ischemia model. Presented Doppler images in experiment group animals taken at day 14; chart reflects dynamics of limb perfusion in untreated negative control (n = 9) or animals that received transplantation of VEGF-expressing (VEGF-ADSC CS, n = 7), mock-transduced CS (ADSC CS, n = 7) or suspended mock-transduced mADSC by intramuscular injection (ADSC inj, n = 7). *p < 0.025 vs. untreated control; **p = 0.007 vs. untreated control and p = 0.038 vs. ADSC CS; #p = 0.01 vs. ADSC injection. Mann–Whitney U test. VEGF vascular endothelial growth factor, CS cell sheet, ADSC adipose-derived stromal cells

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Stem Cell Research & Therapy

ISSN: 1757-6512