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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Aspirin promotes bone marrow mesenchymal stem cell-based calvarial bone regeneration in mini swine

Fig. 3

Aspirin promotes BMSC-based calvarial bone regeneration in mini swine shown by microcomputed tomography (microCT) images. Two freshly created calvarial bone defects were created in each mini swine before they were filled with nothing, HA/TCP, HA/TCP + BMSC treated with or without 75 μg/ml aspirin a-d. MicroCT images of calvarial defect areas were captured two days e-h and six months postsurgery i-l, showing new bone generation in the untreated group e and i, HA/TCP group f and j, HA/TCP + BMSC g and k and HA/TCP + BMSC-aspirin h and l. Quantitative examination of microCT images illustrated relative new bone density between different groups six months postsurgery m. Results are expressed as mean ± standard deviation (SD) and statistical significance is shown as (*) p < 0.05 or (**) p < 0.01. BMSC bone marrow mesenchymal stem cells, HA/TCP hydroxyapatite/tricalcium phosphate

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