Fig. 6
From: Aspirin promotes bone marrow mesenchymal stem cell-based calvarial bone regeneration in mini swine
Aspirin treatment reduced levels of tumor necrosis factor-α (TNF-α) and interferon-γ (IFN-γ) in mini swine calvarial bone defects. Aspirin pretreatment significantly decreased the concentration of TNF-α a and IFN-γ b compared to the HA/TCP-BMSC group. BMSC treatment reduced the concentration IFN-γ in the calvarial bone defect b but not that of TNF-α a. The results are representative of at least three independent experiments. Results are expressed as mean ± standard deviation (SD) and statistical significance is shown as (*) p < 0.05 or (**) p < 0.01. HA/TCP hydroxyapatite/tricalcium phosphate, BMSC bone marrow mesenchymal stem cells