Fig. 7

Serum lipid levels and gene expression in livers at 6 weeks after treatment. Serum TG (a) and HDL (b) levels were measured in CHOW, DIO, or DIO + ASC mice at 6 weeks after ASC infusion. Relative mRNA expression of InsR (c), PPARγ (d), IL-6 (e), F4/80 (f), and NOD2 (g) in livers of CHOW, DIO, and DIO + ASC mice as measured by reverse transcription-polymerase chain reaction analysis. Values represent relative expression of target gene relative to GAPDH (glyceraldehyde 3-phosphate dehydrogenase) control (National Institutes of Health ImageJ software). Samples from five or six individual mice were analyzed. Data are mean ± standard deviation; *P < 0.05 and **P < 0.01, one-way analysis-of-variance test. (h). Relative expression of GFP in livers harvested from CHOW, DIO, and DIO + ASC mice at 7 and 14 days after cell injection. ASC adipose-derived stem cell, CHOW mice fed standard diet, DIO diet-induced obese mice treated with vehicle