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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Transplantation of human adipose stem cell-derived hepatocyte-like cells with restricted localization to liver using acellular amniotic membrane

Fig. 3

Expression levels of hepatocyte function-specific genes in hASC-HLCs plated on 2D-AHAM and 3D-AHAM. Real-time RT-PCR was used to analyze the expression of hepatocyte function-specific genes in hASC-HLCs plated on 2D-AHAM and 3D-AHAM (represented as 2D and 3D, respectively) on day 3. The freshly differentiated hASC-HLCs and human hepatocytes were used as controls. The relative expression of each gene was normalized to 18S rRNA. Statistically significant compared with the 2D-AHAM (p <0.05). *Statistically significant compared with the 2D-AHAM and the freshly differentiated hASC-HLCs (p <0.05). **Statistically significant compared with the 2D-AHAM, the freshly differentiated hASC-HLCs, and human hepatocytes (p <0.05). #Statistically significant compared with the freshly differentiated hASC-HLCs and human hepatocytes (p <0.05). AHAM acellular human amniotic membrane, APOC1 apolipoprotein C-I, CPS1 carbamoyl-phosphate synthase 1, CYP1A2 cytochrome P450 1A2, CYP2B6 cytochrome P450 2B6, CYP2E1 cytochrome P450 2E1, CYP3A4 cytochrome P450 3A4, CYP7A1 cytochrome P450 7A1, hASC human adipose stem cell, HLC hepatocyte-like cell, PCK2 phosphoenolpyruvate carboxykinase 2

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