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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Adenovirus-mediated transfer of hepatocyte growth factor gene to human dental pulp stem cells under good manufacturing practice improves their potential for periodontal regeneration in swine

Fig. 2

hDPSCs that overexpressed HGF prevented apoptosis and promoted neovascularization in vivo. a, b Representative photomicrographs of histological sections of periodontal soft tissues from a the hDPSC injection group and b the HGF-hDPSC injection group. Blue arrows, location of capillaries. c The number of capillaries in ischemic periodontal soft tissues was significantly higher in the HGF-hDPSC injection group compared with the hDPSC group (*P <0.05). d Annexin V staining for apoptosis showed that more apoptotic cells were found in the hDPSC injection group than in the HGF-hDPSC injection group (*P <0.05). hDPSC human dental pulp stem cell, HGF hepatocyte growth factor

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Stem Cell Research & Therapy

ISSN: 1757-6512