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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Inhibition of Oct 3/4 mitigates the cardiac progenitor-derived myocardial repair in infarcted myocardium

Fig. 4

Inhibition of Oct3/4 mitigated CSC-derived myocardium regeneration and angiogenesis in post-MI heart. Representative images of CD31 (a) and α-SMA (b) staining in post-MI hearts, respectively. c, d Quantitative analysis of c-kit+ CSC-derived angiogenetic response. Results were indicated by the number of CD31-positive or α-SMA-positive cells per mm2. Values shown as mean ± SEM (n = 4 per group); #p <0.05 vs. MI + CSCs-Oct3/4(+) control siRNA, ##p <0.01 vs. MI + CSCs-Oct3/4(+) control siRNA. Scale bar: 100 μm. CSC cardiac stem cell, DAPI 4,6-diamidino-2-phenylindole, GFP green fluorescent protein, MI myocardial infarction, siRNA small interfering RNA

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