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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Allogeneic guinea pig mesenchymal stem cells ameliorate neurological changes in experimental colitis

Fig. 5

Effects of guinea pig MSC treatments on leukocyte infiltration in the colonic wall. a–d′ CD45-IR leukocytes were visualised within the mucosa, submucosa and muscle layers of the colon. Cross-sections from guinea pig colon collected at 24 h (a–d) and 72 h (a′–d′) after treatment. Scale bar = 100 μm. e All of the CD45-IR cells were quantified in the mucosa, submucosa and muscle layers within a 650-μm2 area of the colon. *P <0.05, ***P <0.001, ****P <0.0001, significantly different from sham; †P <0.05, ††P <0.01, †††P <0.001, ††††P <0.0001, significantly different from TNBS; n = 4 animals per group per time point. gpAT-MSC guinea pig adipose tissue-derived mesenchymal stem cell, gpBM-MSC guinea pig bone marrow-derived mesenchymal stem cell, MSC mesenchymal stem cell, TNBS 2,4,6-trinitrobenzene sulfonic acid

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