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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Allogeneic guinea pig mesenchymal stem cells ameliorate neurological changes in experimental colitis

Fig. 6

Effects of treatments with guinea pig MSCs on leukocyte infiltration to the myenteric plexus. a–d′ CD45-IR leukocytes (green) were visualised on the level of myenteric neurons labelled with anti-PGP9.5 (red) by confocal microscopy. Wholemounts of the myenteric plexus from guinea pig colon preparations collected at 24 h (a–d) and 72 h (a′-d′) after treatment. Scale bar = 50 μm. e CD45-IR leukocytes were quantified in a 2-mm2 area of the myenteric plexus in the colon. **P <0.01, ***P <0.001, ****P <0.0001, n = 4 animals per group per time point. gpAT-MSC guinea pig adipose tissue-derived mesenchymal stem cell, gpBM-MSC guinea pig bone marrow-derived mesenchymal stem cell, MSC mesenchymal stem cell, PGP9.5 protein gene product 9.5

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