Fig. 9
From: Allogeneic guinea pig mesenchymal stem cells ameliorate neurological changes in experimental colitis
Effects of guinea pig MSCs on cholinergic myenteric neurons. a–d′ Cholinergic (ChAT-IR) neurons in the myenteric plexus at 24 h (a–d) and 72 h (a′-d′). Scale bar = 50 μm. The total number of ChAT-IR neurons (e) and the proportion of ChAT-IR neurons to the total number of HuC/D-IR neurons (f) were quantified within a 2-mm2 area of the myenteric plexus in the guinea pig colon. *P <0.05, **P <0.01, ***P <0.001, n = 4 animals per group per time point. gpAT-MSC guinea pig adipose tissue-derived mesenchymal stem cell, gpBM-MSC guinea pig bone marrow-derived mesenchymal stem cell, MSC mesenchymal stem cell, TNBS 2,4,6-Trinitrobenzene sulfonic acid