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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Comparison of intraspinal and intrathecal implantation of induced pluripotent stem cell-derived neural precursors for the treatment of spinal cord injury in rats

Fig. 1

Functional motor recovery evaluated by the BBB test a. Statistical differences between the appropriate control and cell-treated groups are indicated by *p <0.05 and **p <0.01. The sensitivity of the hind paws to thermal stimuli was examined by the Plantar test b. The withdrawal latency before surgery is represented by the two left-most columns in the figure. There were no significant differences between the controls and the iPS-NP-treated groups throughout the experiment. The flat beam scores evaluate the locomotor function of the hind legs c. The maximum score is 7 in a healthy animal. The differences between the i.s. control and cell-treated groups were always significant (**p <0.01 above the gray columns). Locomotor ability to traverse a beam with a flat surface d. The latency decreased week by week in the treated groups when compared with the control groups. Statistical differences between the appropriate control and cell-treated groups are indicated: *p <0.05 and **p <0.01. BBB Basso, Beattie, and Bresnahan, iPS induced pluripotent stem cell, SCI spinal cord injury, W weeks, Tx day of transplantation

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