TY - JOUR AU - Madry, H. AU - Dijk, C. N. AU - Mueller-Gerbl, M. PY - 2010 DA - 2010// TI - The basic science of the subchondral bone JO - Knee Surg Sports Traumatol Arthrosc. VL - 18 UR - https://doi.org/10.1007/s00167-010-1054-z DO - 10.1007/s00167-010-1054-z ID - Madry2010 ER - TY - JOUR AU - Orth, P. AU - Rey-Rico, A. AU - Venkatesan, J. K. AU - Madry, H. AU - Cucchiarini, M. PY - 2014 DA - 2014// TI - Current perspectives in stem cell research for knee cartilage repair JO - Stem Cells Cloning. VL - 7 ID - Orth2014 ER - TY - JOUR AU - Breinan, H. A. AU - Martin, S. D. AU - Hsu, H. P. AU - Spector, M. PY - 2000 DA - 2000// TI - Healing of canine articular cartilage defects treated with microfracture, a type-II collagen matrix, or cultured autologous chondrocytes JO - J Orthop Res. VL - 18 UR - https://doi.org/10.1002/jor.1100180516 DO - 10.1002/jor.1100180516 ID - Breinan2000 ER - TY - JOUR AU - Frisbie, D. D. AU - Oxford, J. T. AU - Southwood, L. AU - Trotter, G. W. AU - Rodkey, W. G. AU - Steadman, J. R. PY - 2003 DA - 2003// TI - Early events in cartilage repair after subchondral bone microfracture JO - Clin Orthop Relat Res. VL - 407 UR - https://doi.org/10.1097/00003086-200302000-00031 DO - 10.1097/00003086-200302000-00031 ID - Frisbie2003 ER - TY - JOUR AU - Wakitani, S. AU - Mitsuoka, T. AU - Nakamura, N. AU - Toritsuka, Y. AU - Nakamura, Y. AU - Horibe, S. PY - 2004 DA - 2004// TI - Autologous bone marrow stromal cell transplantation for repair of full-thickness articular cartilage defects in human patellae: two case reports JO - Cell Transplant. VL - 13 UR - https://doi.org/10.3727/000000004783983747 DO - 10.3727/000000004783983747 ID - Wakitani2004 ER - TY - JOUR AU - Kuroda, R. AU - Ishida, K. AU - Matsumoto, T. AU - Akisue, T. AU - Fujioka, H. AU - Mizuno, K. PY - 2007 DA - 2007// TI - Treatment of a full-thickness articular cartilage defect in the femoral condyle of an athlete with autologous bone-marrow stromal cells JO - Osteoarthritis Cartilage. VL - 15 UR - https://doi.org/10.1016/j.joca.2006.08.008 DO - 10.1016/j.joca.2006.08.008 ID - Kuroda2007 ER - TY - JOUR AU - Wakitani, S. AU - Nawata, M. AU - Tensho, K. AU - Okabe, T. AU - Machida, H. AU - Ohgushi, H. PY - 2007 DA - 2007// TI - Repair of articular cartilage defects in the patello-femoral joint with autologous bone marrow mesenchymal cell transplantation: three case reports involving nine defects in five knees JO - J Tissue Eng Regen Med. VL - 1 UR - https://doi.org/10.1002/term.8 DO - 10.1002/term.8 ID - Wakitani2007 ER - TY - JOUR AU - Haleem, A. M. AU - Singergy, A. A. AU - Sabry, D. AU - Atta, H. M. AU - Rashed, L. A. AU - Chu, C. R. PY - 2010 DA - 2010// TI - The clinical use of human culture-expanded autologous bone marrow mesenchymal stem cells transplanted on platelet-rich fibrin glue in the treatment of articular cartilage defects: a pilot study and preliminary results JO - Cartilage. VL - 1 UR - https://doi.org/10.1177/1947603510366027 DO - 10.1177/1947603510366027 ID - Haleem2010 ER - TY - JOUR AU - Nejadnik, H. AU - Hui, J. H. AU - Feng Choong, E. P. AU - Tai, B. C. AU - Lee, E. H. PY - 2010 DA - 2010// TI - Autologous bone marrow-derived mesenchymal stem cells versus autologous chondrocyte implantation: an observational cohort study JO - Am J Sports Med. VL - 38 UR - https://doi.org/10.1177/0363546509359067 DO - 10.1177/0363546509359067 ID - Nejadnik2010 ER - TY - JOUR AU - Skowroński, J. AU - Rutka, M. PY - 2013 DA - 2013// TI - Osteochondral lesions of the knee reconstructed with mesenchymal stem cells—results JO - Ortop Traumatol Rehabil. VL - 15 ID - Skowroński2013 ER - TY - JOUR AU - Johnstone, B. AU - Alini, M. AU - Cucchiarini, M. AU - Dodge, G. R. AU - Eglin, D. AU - Guilak, F. PY - 2013 DA - 2013// TI - Tissue engineering for articular cartilage repair—the state of the art JO - Eur Cell Mater. VL - 25 ID - Johnstone2013 ER - TY - JOUR AU - Frisch, J. AU - Venkatesan, J. K. AU - Rey-Rico, A. AU - Madry, H. AU - Cucchiarini, M. PY - 2015 DA - 2015// TI - Current progress in stem cell-based gene therapy for articular cartilage repair JO - Curr Stem Cell Res Ther. VL - 10 UR - https://doi.org/10.2174/1574888X09666140922112326 DO - 10.2174/1574888X09666140922112326 ID - Frisch2015 ER - TY - JOUR AU - Ikeda, T. AU - Kamekura, S. AU - Mabuchi, A. AU - Kou, I. AU - Seki, S. AU - Takato, T. PY - 2004 DA - 2004// TI - The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage JO - Arthritis Rheum. VL - 50 UR - https://doi.org/10.1002/art.20611 DO - 10.1002/art.20611 ID - Ikeda2004 ER - TY - JOUR AU - Pagnotto, M. R. AU - Wang, Z. AU - Karpie, J. C. AU - Ferretti, M. AU - Xiao, X. AU - Chu, C. R. PY - 2007 DA - 2007// TI - Adeno-associated viral gene transfer of transforming growth factor-beta1 to human mesenchymal stem cells improves cartilage repair JO - Gene Ther. VL - 14 UR - https://doi.org/10.1038/sj.gt.3302938 DO - 10.1038/sj.gt.3302938 ID - Pagnotto2007 ER - TY - JOUR AU - Babister, J. C. AU - Tare, R. S. AU - Green, D. W. AU - Inglis, S. AU - Mann, S. AU - Oreffo, R. O. PY - 2008 DA - 2008// TI - Genetic manipulation of human mesenchymal progenitors to promote chondrogenesis using “bead-in-bead” polysaccharide capsules JO - Biomaterials. VL - 29 UR - https://doi.org/10.1016/j.biomaterials.2007.09.006 DO - 10.1016/j.biomaterials.2007.09.006 ID - Babister2008 ER - TY - JOUR AU - Cucchiarini, M. AU - Ekici, M. AU - Schetting, S. AU - Kohn, D. AU - Madry, H. PY - 2011 DA - 2011// TI - Metabolic activities and chondrogenic differentiation of human mesenchymal stem cells following recombinant adeno-associated virus-mediated gene transfer and overexpression of fibroblast growth factor 2 JO - Tissue Eng Part A. VL - 17 UR - https://doi.org/10.1089/ten.tea.2011.0018 DO - 10.1089/ten.tea.2011.0018 ID - Cucchiarini2011 ER - TY - JOUR AU - Kim, H. J. AU - Im, G. I. PY - 2011 DA - 2011// TI - Electroporation-mediated transfer of SOX trio genes (SOX-5, SOX-6, and SOX-9) to enhance the chondrogenesis of mesenchymal stem cells JO - Stem Cells Dev. VL - 20 UR - https://doi.org/10.1089/scd.2010.0516 DO - 10.1089/scd.2010.0516 ID - Kim2011 ER - TY - JOUR AU - Lee, H. H. AU - Haleem, A. M. AU - Yao, V. AU - Li, J. AU - Xiao, X. AU - Chu, C. R. PY - 2011 DA - 2011// TI - Release of bioactive adeno-associated virus from fibrin scaffolds: effects of fibrin glue concentrations JO - Tissue Eng Part A. VL - 17 UR - https://doi.org/10.1089/ten.tea.2010.0586 DO - 10.1089/ten.tea.2010.0586 ID - Lee2011 ER - TY - JOUR AU - Liu, T. M. AU - Guo, X. M. AU - Tan, H. S. AU - Hui, J. H. AU - Lim, B. AU - Lee, E. H. PY - 2011 DA - 2011// TI - Zinc-finger protein 145, acting as an upstream regulator of SOX9, improves the differentiation potential of human mesenchymal stem cells for cartilage regeneration and repair JO - Arthritis Rheum. VL - 63 UR - https://doi.org/10.1002/art.30430 DO - 10.1002/art.30430 ID - Liu2011 ER - TY - JOUR AU - Haleem-Smith, H. AU - Calderon, R. AU - Song, Y. AU - Tuan, R. S. AU - Chen, F. H. PY - 2012 DA - 2012// TI - Cartilage oligomeric matrix protein enhances matrix assembly during chondrogenesis of human mesenchymal stem cells JO - J Cell Biochem. VL - 113 UR - https://doi.org/10.1002/jcb.23455 DO - 10.1002/jcb.23455 ID - Haleem-Smith2012 ER - TY - JOUR AU - Steinert, A. F. AU - Weissenberger, M. AU - Kunz, M. AU - Gilbert, F. AU - Ghivizzani, S. C. AU - Göbel, S. PY - 2012 DA - 2012// TI - Indian hedgehog gene transfer is a chondrogenic inducer of human mesenchymal stem cells JO - Arthritis Res Ther. VL - 14 UR - https://doi.org/10.1186/ar3921 DO - 10.1186/ar3921 ID - Steinert2012 ER - TY - JOUR AU - Venkatesan, J. K. AU - Ekici, M. AU - Madry, H. AU - Schmitt, G. AU - Kohn, D. AU - Cucchiarini, M. PY - 2012 DA - 2012// TI - SOX9 gene transfer via safe, stable, replication-defective recombinant adeno-associated virus vectors as a novel, powerful tool to enhance the chondrogenic potential of human mesenchymal stem cells JO - Stem Cell Res Ther. VL - 3 UR - https://doi.org/10.1186/scrt113 DO - 10.1186/scrt113 ID - Venkatesan2012 ER - TY - JOUR AU - Frisch, J. AU - Venkatesan, J. K. AU - Rey-Rico, A. AU - Schmitt, G. AU - Madry, H. AU - Cucchiarini, M. PY - 2014 DA - 2014// TI - Determination of the chondrogenic differentiation processes in human bone marrow-derived mesenchymal stem cells genetically modified to overexpress transforming growth factor-β via recombinant adeno-associated viral vectors JO - Hum Gene Ther. VL - 25 UR - https://doi.org/10.1089/hum.2014.091 DO - 10.1089/hum.2014.091 ID - Frisch2014 ER - TY - JOUR AU - Liu, S. AU - Zhang, E. AU - Yang, M. AU - Lu, L. PY - 2014 DA - 2014// TI - Overexpression of Wnt11 promotes chondrogenic differentiation of bone marrow-derived mesenchymal stem cells in synergism with TGF-β JO - Mol Cell Biochem. VL - 390 UR - https://doi.org/10.1007/s11010-014-1963-0 DO - 10.1007/s11010-014-1963-0 ID - Liu2014 ER - TY - JOUR AU - Steinert, A. F. AU - Palmer, G. D. AU - Pilapil, C. AU - Nöth, U. AU - Evans, C. H. AU - Ghivizzani, S. C. PY - 2009 DA - 2009// TI - Enhanced in vitro chondrogenesis of primary mesenchymal stem cells by combined gene transfer JO - Tissue Eng Part A. VL - 15 UR - https://doi.org/10.1089/ten.tea.2007.0252 DO - 10.1089/ten.tea.2007.0252 ID - Steinert2009 ER - TY - JOUR AU - Jeon, S. Y. AU - Park, J. S. AU - Yang, H. N. AU - Woo, D. G. AU - Park, K. H. PY - 2012 DA - 2012// TI - Co-delivery of SOX9 genes and anti-Cbfa-1 siRNA coated onto PLGA nanoparticles for chondrogenesis of human MSCs JO - Biomaterials. VL - 33 UR - https://doi.org/10.1016/j.biomaterials.2012.02.051 DO - 10.1016/j.biomaterials.2012.02.051 ID - Jeon2012 ER - TY - JOUR AU - Liu, P. AU - Sun, L. AU - Chen, H. AU - Sun, S. AU - Zhou, D. AU - Pang, B. PY - 2015 DA - 2015// TI - Lentiviral-mediated multiple gene transfer to chondrocytes promotes chondrocyte differentiation and bone formation in rabbit bone marrow-derived mesenchymal stem cells JO - Oncol Rep. VL - 34 ID - Liu2015 ER - TY - JOUR AU - Cucchiarini, M. AU - Terwilliger, E. F. AU - Kohn, D. AU - Madry, H. PY - 2009 DA - 2009// TI - Remodelling of human osteoarthritic cartilage by FGF-2, alone or combined with Sox9 via rAAV gene transfer JO - J Cell Mol Med. VL - 13 UR - https://doi.org/10.1111/j.1582-4934.2008.00474.x DO - 10.1111/j.1582-4934.2008.00474.x ID - Cucchiarini2009 ER - TY - JOUR AU - Johnstone, B. AU - Hering, T. M. AU - Caplan, A. I. AU - Goldberg, V. M. AU - Yoo, J. U. PY - 1998 DA - 1998// TI - In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells JO - Exp Cell Res. VL - 238 UR - https://doi.org/10.1006/excr.1997.3858 DO - 10.1006/excr.1997.3858 ID - Johnstone1998 ER - TY - JOUR AU - Mackay, A. M. AU - Beck, S. C. AU - Murphy, J. M. AU - Barry, F. P. AU - Chichester, C. O. AU - Pittenger, M. F. PY - 1998 DA - 1998// TI - Chondrogenic differentiation of cultured human mesenchymal stem cells from marrow JO - Tissue Eng. VL - 4 UR - https://doi.org/10.1089/ten.1998.4.415 DO - 10.1089/ten.1998.4.415 ID - Mackay1998 ER - TY - JOUR AU - Yoo, J. U. AU - Barthel, T. S. AU - Nishimura, K. AU - Solchaga, L. AU - Caplan, A. I. AU - Goldberg, V. M. PY - 1998 DA - 1998// TI - The chondrogenic potential of human bone-marrow-derived mesenchymal progenitor cells JO - J Bone Joint Surg Am. VL - 80 ID - Yoo1998 ER - TY - JOUR AU - Bi, W. AU - Deng, J. M. AU - Zhang, Z. AU - Behringer, R. R. AU - Crombrugghe, B. PY - 1999 DA - 1999// TI - Sox9 is required for cartilage formation JO - Nat Genet. VL - 22 UR - https://doi.org/10.1038/8792 DO - 10.1038/8792 ID - Bi1999 ER - TY - JOUR AU - Barry, F. AU - Boynton, R. E. AU - Liu, B. AU - Murphy, J. M. PY - 2001 DA - 2001// TI - Chondrogenic differentiation of mesenchymal stem cells from bone marrow: differentiation-dependent gene expression of matrix components JO - Exp Cell Res. VL - 268 UR - https://doi.org/10.1006/excr.2001.5278 DO - 10.1006/excr.2001.5278 ID - Barry2001 ER - TY - JOUR AU - Samulski, R. J. AU - Chang, L. S. AU - Shenk, T. PY - 1987 DA - 1987// TI - A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication JO - J Virol. VL - 61 ID - Samulski1987 ER - TY - JOUR AU - Samulski, R. J. AU - Chang, L. S. AU - Shenk, T. PY - 1989 DA - 1989// TI - Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression JO - J Virol. VL - 63 ID - Samulski1989 ER - TY - JOUR AU - Cucchiarini, M. AU - Thurn, T. AU - Weimer, A. AU - Kohn, D. AU - Terwilliger, E. F. AU - Madry, H. PY - 2007 DA - 2007// TI - Restoration of the extracellular matrix in human osteoarthritic articular cartilage by overexpression of the transcription factor SOX9 JO - Arthritis Rheum. VL - 56 UR - https://doi.org/10.1002/art.22299 DO - 10.1002/art.22299 ID - Cucchiarini2007 ER - TY - JOUR AU - Park, J. S. AU - Yang, H. N. AU - Woo, D. G. AU - Jeon, S. Y. AU - Park, K. H. PY - 2012 DA - 2012// TI - SOX9 gene plus heparinized TGF-β 3 coated dexamethasone loaded PLGA microspheres for inducement of chondrogenesis of hMSCs JO - Biomaterials. VL - 33 UR - https://doi.org/10.1016/j.biomaterials.2012.06.023 DO - 10.1016/j.biomaterials.2012.06.023 ID - Park2012 ER - TY - JOUR AU - Liao, J. AU - Hu, N. AU - Zhou, N. AU - Lin, L. AU - Zhao, C. AU - Yi, S. PY - 2014 DA - 2014// TI - Sox9 potentiates BMP2-induced chondrogenic differentiation and inhibits BMP2-induced osteogenic differentiation JO - PLoS One. VL - 9 UR - https://doi.org/10.1371/journal.pone.0089025 DO - 10.1371/journal.pone.0089025 ID - Liao2014 ER - TY - JOUR AU - Cucchiarini, M. AU - Madry, H. AU - Ma, C. AU - Thurn, T. AU - Zurakowski, D. AU - Menger, M. D. PY - 2005 DA - 2005// TI - Improved tissue repair in articular cartilage defects in vivo by rAAV-mediated overexpression of human fibroblast growth factor 2 JO - Mol Ther. VL - 12 UR - https://doi.org/10.1016/j.ymthe.2005.03.012 DO - 10.1016/j.ymthe.2005.03.012 ID - Cucchiarini2005 ER - TY - JOUR AU - Bakker, A. C. AU - Loo, F. A. AU - Beuningen, H. M. AU - Sime, P. AU - Lent, P. L. AU - Kraan, P. M. PY - 2001 DA - 2001// TI - Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation JO - Osteoarthritis Cartilage. VL - 9 UR - https://doi.org/10.1053/joca.2000.0368 DO - 10.1053/joca.2000.0368 ID - Bakker2001 ER - TY - JOUR AU - Mi, Z. AU - Ghivizzani, S. C. AU - Lechman, E. AU - Glorioso, J. C. AU - Evans, C. H. AU - Robbins, P. D. PY - 2003 DA - 2003// TI - Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees JO - Arthritis Res Ther. VL - 5 UR - https://doi.org/10.1186/ar745 DO - 10.1186/ar745 ID - Mi2003 ER -