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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Intraspinal bone-marrow cell therapy at pre- and symptomatic phases in a mouse model of amyotrophic lateral sclerosis

Fig. 2

Gender effect in the functional outcome of SOD-1G93A mice after BMMC therapy. a, b, g Rotarod test, c, d hanging-wire test, and e, f, h motor-score test. Female SOD-1G93A animals that received the treatment in week 9 showed a delay in the functional loss in all tests performed b, d, f. Male animals treated in week 9 showed a delay only in the hanging-wire test c. The therapy in week 14 improved the rotarod performance in males g and delayed the deficit analyzed by motor score grade in BMMC-injected females h. Arrows indicate week of treatment. *WT vs. saline (p <0.05), #WT vs. BMMC (p <0.05). BMMC bone marrow-derived mononuclear cells, WT wild-type

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