Skip to main content
Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Intraspinal bone-marrow cell therapy at pre- and symptomatic phases in a mouse model of amyotrophic lateral sclerosis

Fig. 3

Quantification of motor neurons in the anterior horn of the spinal cord. The number of NeuN-positive cells was quantified in week 12 in the presymptomatic injected animals a and in week 15 in the symptomatic injected animals b. Both saline-injected and BMMC-injected mice showed a decrease in the number of motor neurons compared with the wild-type mice at the time point analyzed. There was no difference in the number of motor neurons after the treatment with BMMC injected in week 9 or in week 14 c–e. Representative images of NeuN expression in wild-type mice c, saline-injected animals in week 9 d, and BMMC-injected animals in week 9 e. *p <0.01. Scale bar: 50 μm. BMMC bone marrow-derived mononuclear cells, WT wild-type

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512