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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Hypoxic conditioned medium from mesenchymal stem cells promotes lymphangiogenesis by regulation of mitochondrial-related proteins

Fig. 2

Increased expression of lymphangiogenic factors of hMSCs in hypoxia. a Expression of lymphangiogenic factors (EGF, FGF, HGF, IGF-1, VEGF-A, and VEGF-C) of hMSCs in hypoxia. Expression of mRNAs was measured using quantitative RT-PCR. Gene expressions were normalized using GAPDH expression, respectively. b, c Expression of VEGF-C and VEGF-A was analyzed using quantitative RT-PCR in EBM, NCM, or HCM-treated hLECs. Control: EBM. Values are represented as the mean of three measurements with the SD indicated by error bars. *p <0.001, # p <0.05. EGF epidermal growth factor, FGF fibroblast growth factor, HCM hypoxic conditioned media, HGF hepatocyte growth factor, IGF insulin-like growth factor, LEC lymphatic endothelial cells, NCM normoxic conditioned media, VEGF vascular endothelial growth factor

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Stem Cell Research & Therapy

ISSN: 1757-6512