Skip to main content
Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Intravitreal administration of multipotent mesenchymal stromal cells triggers a cytoprotective microenvironment in the retina of diabetic mice

Fig. 4

Donor mesenchymal stromal cells (MSCs) remain in the eye at least until 12 weeks after their administration. Twelve weeks after STZ administration, diabetic mice received an intravitreal dose of 2 × 105 MSCsGFP in 2 μL saline. On days 1, 4, 8 and 12 weeks later, the presence of donor cells was assessed in the eye by flow cytometry. a Events in gate R1 represent GFP+ cells. b Data were quantified, and the dotted line represents the detection limit. c Presence of donor cells in the eye was also corroborated by immunofluorescence. Qualitative data are representative of eight eyes per analyzed time. Quantitative data correspond to mean ± SEM of eight eyes per analyzed time. DM Diabetes mellitus, GFP green fluorescent protein

Back to article page