Fig. 8

The intravitreal administration of mesenchymal stromal cells (MSCs) has neutral effect in the electrical response of the retina in diabetes mellitus (DM) mice. Four and 12 weeks after the administration of MSCs or vehicle, the electrical responses of the retina were measured by ERG. a Representative ERG showed decreases in a-wave and b-wave in DM mice and in DM + MSC mice in comparison to normal mice using a stimulus of 0.01 cd · s · m^–2; black line, normal mice; blue line, DM mice; purple line, DM + MSC mice. The a-waves were quantified under scotopic conditions using stimuli of b 0.01 cd · s · m^–2 or c 3.0 cd · s · m^–2. The b-waves were quantified under scotopic conditions using stimuli of d 0.01 cd · s · m^–2 or e 3.0 cd · s · m^–2. f The peak amplitudes of the first six waves of the oscillatory potentials were quantified. Qualitative data are representative of eight eyes per group and per analyzed time. Quantitative data correspond to mean ± SEM of eigth eyes per group and per analyzed time