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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Mesenchymal stem cells and cutaneous wound healing: novel methods to increase cell delivery and therapeutic efficacy

Fig. 1

Enhanced cutaneous wound healing by mesenchymal stem cells. This involves accelerating wound closure, increasing angiogenesis, decreasing wound inflammation, positively regulating extracellular matrix (ECM) remodeling, and promoting regeneration of normal skin architecture and functioning. These effects are mediated via paracrine signaling. GPx glutathione peroxidase, HaCaT immortalized human keratinocyte, HGF hepatocyte growth factor, ICAM1 intercellular adhesion molecule 1, IL-1 interleukin-1, MMP-1 matrix metalloproteinase-1, SOD superoxide dismutase, TNF-α tumor necrosis factor-alpha, VEGF vascular endothelial growth factor

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Stem Cell Research & Therapy

ISSN: 1757-6512