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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Role of VEGF-A in angiogenesis promoted by umbilical cord-derived mesenchymal stromal/stem cells: in vitro study

Fig. 4

Secondary sprouting in Matrigel. a Clusters formed in Matrigel by the EA.hy926 cells and UC-MSC-EA.hy926 cell mix, but not by UC-MSCs alone, became centers of secondary sprouting. Gradually, the isolated sprouting centers joined into a single, very stable 3D network. Scale bar 100 μm. b In a mixed culture network only PKH26-labeled UC-MSCs (red) formed sprouts while PKH67-labeled EA.hy926 cells (green) stayed in the centers of the clusters. Scale bar 100 μm. UC-MSC umbilical cord-derived mesenchymal stromal/stem cell (Color figure online)

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