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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Minicircle DNA-mediated endothelial nitric oxide synthase gene transfer enhances angiogenic responses of bone marrow-derived mesenchymal stem cells

Fig. 6

In vitro tubule formation in eNOS transfected rBMSCs. a Capillary tubule formation in rBMSCs transfected with P-eNOS and MC-eNOS and cytoskeletal staining by Phalloidin TRITC; treatment with the NO inhibitor L-NAME reduces capillary formation. b Quantitation of tubule number. c Measurement of tubule length. *p < 0.05 and **p < 0.05 vs. MC-eNOS (L-NAME), P-eNOS (L-NAME), MC-GFP, P-GFP, and rBMSC. L-NAME, L-NG-nitroarginine methyl ester, MC-eNOS minicircle vector expressing endothelial nitric oxide synthase, MC-GFP minicircle vector expressing green fluorescent protein, P-eNOS plasmid vector expressing endothelial nitric oxide synthase, P-GFP plasmid vector expressing green fluorescent protein, rBMSC rat bone marrow-derived mesenchymal stem cell

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