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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Transplantation of bone marrow-derived mesenchymal stem cells expressing elastin alleviates pelvic floor dysfunction

Fig. 4

bFGF-PLGA promotes the expression and secretion of elastin and collagen in differentiated BMSCs. BMSCs with or without elastin transduction were differentiated in the presence of either bFGF or bFGF-PLGA for 7 days. Levels of mRNA a and protein b, and concentration in medium c of elastin and collagen were examined by RT-PCR, western blot, and ELISA assays. Values are mean ± SD. *P <0.05 vs BMSC + bFGF and BMSC + bFGF-PLGA. #P <0.05 vs elastin-BMSC + bFGF. bFGF basic fibroblast growth factor, BMSC bone marrow-derived mesenchymal stem cell, PLGA poly(lactic-co-glycolic acid)

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Stem Cell Research & Therapy

ISSN: 1757-6512