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Table 1 Baseline clinical characteristics of the patients

From: The impact of patient co-morbidities on the regenerative capacity of cardiac explant-derived stem cells

 

Number of patients (N = 32)

Association with advance LTS score P value ± R 2, as applicable

Age (yrs)

65 ± 2

0.55

BMI

28 ± 1

0.35

Gender (%male)

66 %

0.56

Hypertension

71 %

0.09

Dyslipidemia

69 %

0.12

Current smoker

9 %

0.45*

Former smoker

34 %

Diabetes

34 %

0.0003

HbA1C

0.062 ± 0.01

0.002 (R 2 = 0.4)

Fasting glucose

6.2 ± 0.7

0.18

Thyroid or other endocrine disease

9 %

0.38

Peripheral vascular disease

25 %

0.13

History of MI

34 %

0.01

Valvular heart disease

56 %

0.09

Coronary artery disease

75 %

0.09

Congestive heart failure

16 %

0.28

NYHA class

1.6 ± 0.1

0.94

LV ejection fraction

54 ± 2

0.02 (R 2 = 0.17)

CCS class

1.9 ± 0.1

0.74

Creatinine (umol/L)

83 ± 3

0.14

Medications:

 Anti-platelet/Anti-coagulant

78 %

0.12

 Beta-blocker

56 %

0.38

 Statin

53 %

0.55

 Diuretics

31 %

0.07

 ACEI or ARB

46 %

0.11

 Calcium channel blocker

43 %

0.64

 Insulin

9 %

0.30

 Oral hypoglycemics

31 %

<0.001

  1. LTS long term stratification, BMI body mass index, HbA1C hemoglobin A1c, MI myocardial infarction, NYHA New York Heart Association, LV left ventricle, CCS Canadian Cardiovascular Society, ACEI angiotensin-converting enzyme inhibitors, ARB angiotensin receptor blockers. *p vs. LTS score in non-smokers