Table 1 Statistically evaluated impact of mouse HCN2 to the expression of transcription factors
No | Gene | Main impact to cell cycle regulation | Fold-change | P value |
|---|---|---|---|---|
1. | ATF3 | Delays G1 to S transition [29] | 7.11 | 0.00056 |
2. | ETS2 | Promotes G2/M phase [46] | 2.79 | 0.02 |
3. | GTF2B | Regulates G1 phase [33] | 1.9 | 0.01 |
4. | ID1 | Promotes G1/S phase [37] | 1.86 | 0.044 |
5. | MYC | Promotes G1/S phase [36] | 2.3 | 0.0028 |
6. | NFATC3 | Promotes G1/S phase [41] | 1.6 | 0.02 |
7. | REL | Promotes G0 toG1 transition [45] | 1.94 | 0.014 |
8. | TBP | Delays G2/M phase [24] | 2.04 | 0.012 |
9. | TGIF1 | Promotes G0 toG1 transition [22] | 2.97 | 0.025 |