Fig. 5

Representative images showing mild to severe OA. Representative thionine-stained sections of the median scoring knee from each condition: a vehicle, b Ad-IL10 only, c MSCs only, d AdNull MSCs and e Ad-IL10 MSCs. Erosion of the cartilage, osteophyte formation and synovial hyperplasia is visible in several of the images. Each image illustrates the medial compartment. FC femoral condyle, TC tibial condyle, S synovium, Op osteophyte. Scale bar =250 μm