Skip to main content
Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: EDTA soluble chemical components and the conditioned medium from mobilized dental pulp stem cells contain an inductive microenvironment, promoting cell proliferation, migration, and odontoblastic differentiation

Fig. 1

Pulp regeneration after ectopic tooth root transplantation. Pulp regeneration after ectopic tooth root transplantation in SCID mice. Twenty-eight days after transplantation of MDPSCs with (a, e, j, o) nonextracted tooth, (b, f, k, p) HCl-extracted tooth, (c, g, l, q) GdnHCl-extracted tooth, and (d, h, m, r) EDTA-extracted tooth. a–h H & E staining. Pulp-like cells (arrows). i Ratio of regenerated area to root canal area. j–m Hoechst 33342 staining. n Ratio of Hoechst 33342-positive cells to regenerated area. o–r Immunostaining with rat endothelial cell antigen 1 (RECA1). s Ratio of vascularization area to the total regenerated area. Data are expressed as means ± SD of four determinations. **P < 0.01, ***P < 0.001

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512