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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Combined administration of mesenchymal stem cells overexpressing IGF-1 and HGF enhances neovascularization but moderately improves cardiac regeneration in a porcine model

Fig. 3

a Effect of superparamagnetic iron oxide (SPIO) labeling in pig mesenchymal stem cells from adipose tissue (paMSC) viability. paMSC were transduced with pRRLsin.18.CMV-IRES-GFP or were mock-transduced. Both populations were SPIO-labeled (day 0), followed by weekly trypan blue exclusion analysis for 1 month. paMSC mock-transduced (left panel) or paMSC-transduced cells (right panel); SPIO-labeled cells (pink lines) in comparison with mock cells (blue lines). Results are shown as viability (%). b RT-qPCR gene expression profile of transduced paMSC. paMSC populations were analyzed by RT-qPCR at similar passages (n = 2). For those used in the in vivo evaluation, results are shown as the mean of all values. Color scale indicates relative expression values

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