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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Combined administration of mesenchymal stem cells overexpressing IGF-1 and HGF enhances neovascularization but moderately improves cardiac regeneration in a porcine model

Fig. 5

AMI evolution monitored by MRI. a Image sequence for a representative animal from each study group at the four follow-up times. Images were taken on the short axis in the T2 format. b Cardiac function studies. Left ventricle ejection fraction (LVEF), cardiac output (CO), stroke volume (SV), and heart rate (beats/minute) were analyzed. c Numerical data of cardiac function parameters and infarcted area. d Infarcted area evaluation. This graph shows the results obtained (%) after analyzing the infarcted area by MR images during a month of monitoring. On the x axis for b and c, 1, 2, 3, and 4 indicate follow-up times as described in Fig. 4c (*p ≤ 0.05). GFP green fluorescent protein, HGF hepatocyte growth factor, IGF-1 insulin-like growth factor-1, paMSC pig mesenchymal stem cells from adipose tissue

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