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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Transcriptional profiling reveals intrinsic mRNA alterations in multipotent mesenchymal stromal cells isolated from bone marrow of newly-diagnosed type 1 diabetes patients

Fig. 4

VCAM-1 and other adhesion-related molecules are differentially regulated in T1D-MSCs. a Heatmap of adhesion-related genes differentially expressed between MSCs from healthy donors (Controls, n = 4) and T1D patients (Diabetic, n = 4) (FC > 2, p < 0.05, Student t test, Benjamini Hochberg correction). Upregulated genes are shown in red and downregulated genes in green. b Relative expression of VCAM1 by real-time PCR (Diabetic, n = 7; Control, n = 6). Mann-Whitney U test, p = 0.0041. VCAM-1 vascular cell adhesion protein 1

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Stem Cell Research & Therapy

ISSN: 1757-6512