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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Characterization of intercellular communication and mitochondrial donation by mesenchymal stromal cells derived from the human lung

Fig. 5

BM-MSCs, LT-MSCs and BAL-MSCs donate mitochondria to BEAS2B epithelial cells. Bone marrow-derived mesenchymal stromal cells (BM-MSCs, a), lung tissue-derived mesenchymal stromal cells (LT-MSCs, b) and bronchoalveolar fluid-derived mesenchymal stromal cells (BAL-MSCs, c) were cultured with either dynasore to inhibit endocytosis, cytochalasin D to inhibit microtubule/nanotube formation, carbenoxolone to inhibit all gap junction formation or GAP26 to inhibit connexin-43 gap junction formation. Y axis represents this change in mean fluorescent intensity (MFI, %) relative to a paired, uninhibited control. Horizontal line represents median. Groups were compared using the Mann–Whitney U test. *p < 0.05 compared with baseline

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