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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Adipose tissue-derived stem cells suppress hypertrophic scar fibrosis via the p38/MAPK signaling pathway

Fig. 3

The effect of ADSC-CM on cultured HS tissues ex vivo. a The histology and morphology structure of HS tissues were measured by Masson’s trichrome staining for labeling collagen fibers blue after stimulation with 80 % concentration of ADSC-CM or DMEM for 7 days. Scale bar = 100 μm or 50 μm as indicated. be Western blotting analysis for Col1, Col3, and α-SMA in HS tissues cultured with an 80 % concentration of ADSC-CM or DMEM. Quantitative analysis is shown by histogram. Every experiment was repeated three times at least. The data are shown as mean ± SEM (*P < 0.05; **P < 0.01). ADSC-CM adipose tissue-derived stem cell-conditioned medium, Col1 collagen I, Col3 collagen III, DMEM Dulbecco’s modified Eagle medium, SMA smooth muscle actin

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