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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: High-efficiency generation of induced pluripotent mesenchymal stem cells from human dermal fibroblasts using recombinant proteins

Fig. 3

WGBS revealed CpG methylation alterations in iPMSCs compared with fibroblast cells. a Volcano plot depicting the DMRs in iPMSCs compared with fibroblasts (Fib), with the horizontal axis representing methylation differences and the vertical axis representing the standard deviation (sd) in t statistics. b Box plot showing the distribution of CpG sites based on different methylation levels. c Bar plot showing the enrichment of DMRs in different genomic features. d Distribution of DMR distances to its closest TSS; controls are generated by randomly sampling 60,000 regions of 200 bp from hg19

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Stem Cell Research & Therapy

ISSN: 1757-6512