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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Periodontal regeneration in swine after cell injection and cell sheet transplantation of human dental pulp stem cells following good manufacturing practice

Fig. 1

Location of injected hDPSCs and hDPSC sheet under good manufacturing practice. After the injection of iodinated contrast media, axial (a) and sagittal (b) CT slice images demonstrate the aggregation of contrast medium in mandible bone defects (yellow blocks in red dotted line), which indicated the location of injected hDPSCs beneath the periosteum. c The hDPSCs, induced with 20.0 μg/mL Vc, form a morphologically complete cell sheet; the cell sheet contained five or six layers and the cells contacted with each other tightly. d Scanning electron microscopy (SEM) of a hDPSC sheet. Morphologically, the hDPSC sheet was wave-shaped. e SEM of a hDPSC sheet (×1000), all cells contacted each other tightly. f Transmission electron microscopy (TEM) of a hDPSC sheet. Endogenous ECM (ellipse) was observed between cells

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