Fig. 7

CD31-positive cells analyzed by flow cytometry. As a negative control, HFs did not contain the CD31⁺ population (a). In the normoxia condition, ETV2 transduced HFs contained a small CD31⁺ cell population (b). A larger population of CD31⁺ cells was present in ETV2 transduced HFs under hypoxia (d), similar to the ETV2 transduced HFs under normoxia supplemented with VEGF (c). The percentage of CD31⁺ cells significantly decreased in the ETV2 transduced HFs under hypoxia supplemented with anti-VEGF monoclonal antibody (e). VEGF vascular endothelial growth factor. SSC Side Scatter