Fig. 8

CD31 expression in ETV2 transduced fibroblasts. ETV2 transduction under the hypoxia condition (p–t) significantly increased CD31⁺ cells compared with normoxia (a–e), but significantly decreased if the medium was supplemented with anti-VEGF monoclonal antibodies (k–o). In the normoxia condition, adding VEGF to the medium culture of ETV2 transduced cells could significantly increase the CD31⁺ cells (f–j). VEGF vascular endothelial growth factor