Fig. 1

Human umbilical cord-derived mesenchymal stem cell (hUC-MSC) therapy protects against TNBS-induced colitis. HUC-MSC therapy increased the survival rate of experimental colitis mice (a), decreased weight loss (b and c), alleviated colitis symptoms (d), and improved macroscopic (e) and histologic (f) scores. Myeloperoxidase (MPO) activity is shown in (g), and pictures of the colon (h) with hematoxylin and eosin staining (i) of each group are presented. The colon length which can reflect the inflammation was shown in (j). n = 20 for colitis model and treatment groups; n = 10 for model control and naïve mice; ^* P < 0.05 vs. MSC-treated mice. TNBS trinitrobenzenesulfonic acid