Skip to main content
Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Human umbilical cord-derived mesenchymal stem cells protect against experimental colitis via CD5+ B regulatory cells

Fig. 3

hUC-MSCs alter numbers of regulatory T cells (Tregs) in colitis mice. Lymphocytes were co-stained with anti-CD4 and anti-FoxP3 antibodies and evaluated by flow cytometry. Tregs were defined as CD4+FoxP3+. The frequency of Tregs from the hUC-MSC-treated group was significantly lower than that in controls. Representative dot plots of Tregs in the spleen (a) and mesenteric lymph node (MLN) (c) of each group. Treg proportions are shown in (b) and (d). Data are presented as plots with P value. n = 9 for each group; * P < 0.05 vs. MSC-treated mice. hUC-MSC human umbilical cord-derived mesenchymal stem cell, TNBS trinitrobenzenesulfonic acid

Back to article page