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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: C-reactive protein can upregulate VEGF expression to promote ADSC-induced angiogenesis by activating HIF-1α via CD64/PI3k/Akt and MAPK/ERK signaling pathways

Fig. 1

CRP did not affect ADSC apoptosis or proliferation but slightly increased migration via the PI3K/Akt pathway. a Proliferation determined by a CCK-8 assay of ADSC cultures 24, 48, and 72 hours after addition of CRP. b Distribution of the cell cycle phase of ADSCs in 24-hour cultures with or without CRP treatment. c CRP increased the migration of ADSCs and inhibition of Akt (LY294002) significantly inhibited ADSC migration. Data represent mean ± SE (n = 3). Columns, mean; error bars, SEM; *p < 0.05. Results are representative of three independent experiments. CRP C-reactive protein, FBS fetal bovine serum, OD optical density

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