Fig. 2
Expansion potential of MSCs from BM, UCT and AT. a The expansion of MSCs from ten samples of each source (BM, UCT, AT) revealed a high inter-individual variability in the amount of MSCs obtained per gram of initial tissue, which ranged between 2 × 106 and 80 × 106 at Passage 2 (P2). b Comparison of the average of MSCs cumulative cell yield per gram of initial tissue (BM, UCT, AT) at Passage 1 (P1) and P2. Results were represented as mean ± SEM (standard error of the mean) (F = 19.712 and p < 0.000 at ANOVA; *p = 0.008 for AT vs BM and p = 0.001 for AT vs UCT at Scheffe test). c Comparison of the population doubling time (PTD) mean calculated at P1 and P2 of MSCs populations derived from the different tissues. Data are shown as means ± SD of ten samples processed for each tissue (F = 3.960 and p = 0.002 at ANOVA and *p = 0.042 for UCT vs BM and # p = 0.050 for AT vs BM at Scheffe test for P2). AT adipose tissue, BM bone marrow, MSCs mesenchymal stromal cells, UCT umbilical cord tissue